abstract：INTRODUCTION:Although magnesium plays an important role in aerobic metabolism and magnesium deficiency is a common phenomenon in critical illness, the association between magnesium deficiency and lactic acidosis in the intensive care unit (ICU) has not been defined. METHODS:This was a retrospective, cross-sectional st...

journal_title：Journal of intensive care medicine

authors： Moskowitz A,Lee J,Donnino MW,Mark R,Celi LA,Danziger J

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:The strategy used to improve effective checklist use in intensive care unit (ICU) setting is essential for checklist success. This study aimed to test the hypothesis that an electronic checklist could reduce ICU provider workload, errors, and time to checklist completion, as compared to a paper checklist. METH...

journal_title：Journal of intensive care medicine

authors： Thongprayoon C,Harrison AM,O'Horo JC,Berrios RA,Pickering BW,Herasevich V

更新日期：2016-03-01 00:00:00

abstract：INTRODUCTION:The invasive nature and potential complications associated with pulmonary artery (PA) catheters (PACs) have prompted the pursuit of less invasive monitoring options. Before implementing new hemodynamic monitoring technologies, it is important to determine the interchangeability of these modalities. This st...

journal_title：Journal of intensive care medicine

authors： Eiferman DS,Davido HT,Howard JM,Gerckens J,Evans DC,Cook CH,Stawicki SP

更新日期：2016-02-01 00:00:00

abstract：:Longitudinal clivus fractures are rare in children, with only 5 cases published in the English literature to date. Clivus fractures, particularly longitudinal type, are associated with high mortality and morbidity. We report a case of longitudinal clivus fracture in a teenager with survival and complete neurological r...

journal_title：Journal of intensive care medicine

authors： Samraj RS,Stalets EL

更新日期：2015-10-01 00:00:00

abstract：:Periodic epileptiform discharges (PEDs) are frequently encountered during continuous electroencephalography monitoring in the intensive care unit. Their implications and management are variable and highly dependent on the clinical context. This article is intended for the nonneurologist intensivist, reviews basic term...

journal_title：Journal of intensive care medicine

authors： Lahiri S,Boro AD,Shiloh AL,Milstein MJ,Savel RH

更新日期：2015-10-01 00:00:00

abstract：:Neurogenic stunned myocardium (NSM) is a triad of transient left ventricular dysfunction, electrocardiogram changes, and elevation in cardiac enzymes, often mimicking a myocardial infarction. It has been described following acute brain injury. The purported mechanism is catecholamine excess resulting in cardiac dysfun...

journal_title：Journal of intensive care medicine

authors： Murthy SB,Shah S,Rao CP,Bershad EM,Suarez JI

更新日期：2015-09-01 00:00:00

abstract：:Primary and acquired abdominal pathology accounts for a significant proportion of sepsis and SIRS in the ICU population. Abdominal processes often present a difficult diagnostic dilemma in the truly critically ill patient who, due to hemodynamic instability or severe acute respiratory distress syndrome (ARDS) requirin...

journal_title：Journal of intensive care medicine

authors： Zemlyak A,Heniford BT,Sing RF

更新日期：2015-07-01 00:00:00

abstract：:Vasopressin has gained wide support as an adjunct vasopressor in patients with septic shock. This agent exerts its vasoconstriction effects through smooth muscle V1 receptors and also has antidiuretic activity via renal V2 receptors. This interaction with the renal V2 receptors results in the integration of aquaporin ...

journal_title：Journal of intensive care medicine

authors： Salazar M,Hu BB,Vazquez J,Wintz RL,Varon J

更新日期：2015-07-01 00:00:00

abstract：:Hypercalcemia may be seen in a variety of clinical settings and often requires intensive management when serum calcium levels are dramatically elevated. All of the many etiologies of mild hypercalcemia can lead to severe hypercalcemia. Knowledge of the physiologic mechanisms involved in maintaining normocalcemia and b...

journal_title：Journal of intensive care medicine

authors： Maier JD,Levine SN

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Isolated shortness of breath in the patient with a history of a malignancy creates a diagnostic challenge and serves as a source of anxiety. Although cancer recurrence is typically the first concern of the patient and the clinician, toxicities of anticancer therapies must also be considered. METHODS:A case ...

journal_title：Journal of intensive care medicine

authors： Clapham KR,Bhimani RD,Cooper JP,Stern TA

更新日期：2015-05-01 00:00:00

abstract：:Thyroid storm, an endocrine emergency first described in 1926, remains a diagnostic and therapeutic challenge. No laboratory abnormalities are specific to thyroid storm, and the available scoring system is based on the clinical criteria. The exact mechanisms underlying the development of thyroid storm from uncomplicat...

journal_title：Journal of intensive care medicine

authors： Chiha M,Samarasinghe S,Kabaker AS

更新日期：2015-03-01 00:00:00

abstract：:Intracerebral hemorrhage (ICH) in patients with oral anticoagulation therapy is an increasingly prevalent problem in large part due to the aging population and the increased use of anticoagulants for patients at high risk of thrombosis. Warfarin has been virtually the only outpatient anticoagulant choice until fairly ...

journal_title：Journal of intensive care medicine

authors： da Silva IR,Provencio JJ

更新日期：2015-02-01 00:00:00

abstract：:Cardiomyopathy secondary to toxic shock syndrome (TSS) is an uncommon but potentially life-threatening problem. We report the case of a 51-year-old male who presented with profound cardiogenic shock and multiorgan failure that could not be managed by conventional therapy with intravenous fluids, vasopressors and inotr...

journal_title：Journal of intensive care medicine

authors： Gabel E,Gudzenko V,Cruz D,Ardehali A,Fink MP

更新日期：2015-02-01 00:00:00

abstract：:We describe the case of a patient with hemolysis-associated Clostridium perfringens septicemia and review all similar cases published in the literature since 1990, with specific focus on the relationship between treatment strategy and survival. We searched PubMed for all published cases of C. perfringens-associated he...

journal_title：Journal of intensive care medicine

authors： Simon TG,Bradley J,Jones A,Carino G

更新日期：2014-11-01 00:00:00

abstract：:Hospital-acquired infections (HAIs) are common in intensive care unit (ICU) patients and are associated with increased morbidity and mortality. There has been an increasing effort to prevent HAIs, and infection control practices are paramount in avoiding these complications. In the last several years, numerous develop...

journal_title：Journal of intensive care medicine

authors： Gandra S,Ellison RT 3rd

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:Methods to optimize positive end-expiratory pressure (PEEP) in acute respiratory distress syndrome (ARDS) remain controversial despite decades of research. The pressure-volume curve (PVC), a graphical ventilator relationship, has been proposed for prescription of PEEP in ARDS. Whether the use of PVC's improves ...

journal_title：Journal of intensive care medicine

authors： Hata JS,Togashi K,Kumar AB,Hodges LD,Kaiser EF,Tessmann PB,Faust CA,Sessler DI

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:To describe intubation practices and duration of mechanical ventilation in children with status asthmaticus admitted from emergency departments (ERs) to pediatric intensive care units (PICUs). DESIGN:Retrospective cohort study using the Virtual PICU Performance System database (VPS, LLC) of children with sta...

journal_title：Journal of intensive care medicine

authors： Shibata S,Khemani RG,Markovitz B

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Morbidity associated with stress ulcer-related bleeding, the cost of medications, and the possible complications associated with stress ulcer prophylaxis are important considerations when prescribing prophylaxis. We prospectively studied the prescription patterns for stress ulcer prophylaxis in patients admi...

journal_title：Journal of intensive care medicine

authors： Frandah W,Colmer-Hamood J,Nugent K,Raj R

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVES:We report the case of a 28-year-old patient with systemic lupus erythematosus (SLE) with rapid onset of dyspnea and hemoptysis found to have diffuse alveolar hemorrhage (DAH) with refractory hypoxemia successfully treated with venovenous extracorporeal membrane oxygenation (ECMO). The discussion includes cli...

journal_title：Journal of intensive care medicine

authors： Patel JJ,Lipchik RJ

更新日期：2014-03-01 00:00:00

abstract：:Left ventricular assist devices (LVADs) and total artificial hearts (TAHs) are surgically implanted as permanent treatment of unrecoverable heart failure. Both LVADs and TAHs are durable mechanical circulatory support (MCS) devices that can prolong patient survival but also alter end-of-life trajectory. The permissibi...

journal_title：Journal of intensive care medicine

authors： Rady MY,Verheijde JL

更新日期：2014-01-01 00:00:00

abstract：:The treatment of sepsis is an ongoing challenge for clinicians; despite the wide choice of effective antibiotics to treat infection, sepsis remains the leading cause of morbidity and mortality for patients admitted to an intensive care unit. Dysregulation of the immune response is now recognized to be a key factor in ...

journal_title：Journal of intensive care medicine

authors： Panagiotou A,Gaiao S,Cruz DN

更新日期：2013-09-01 00:00:00

abstract：INTRODUCTION:Red cell distribution width (RDW) is reflective of systemic inflammation. The objective of this study was to investigate the association between RDW (on day 1 of development of septic shock) and mortality. METHODS:A total of 279 patients with septic shock were included. We categorized the patients into qu...

journal_title：Journal of intensive care medicine

authors： Sadaka F,O'Brien J,Prakash S

更新日期：2013-09-01 00:00:00

abstract：:Video laryngoscopy has demonstrated utility in airway management. For the present case series, we report the use of video laryngoscopy to evaluate the airway of critically ill, mechanically ventilated patients, as a means to reduce the risk of immediate postextubation stridor by assessing the degree of laryngeal edema...

journal_title：Journal of intensive care medicine

authors： Newmark JL,Ahn YK,Adams MC,Bittner EA,Wilcox SR

更新日期：2013-01-01 00:00:00

abstract：:Diabetes mellitus (DM) represents an enormous health care concern for the United States and other countries. According to the American Diabetes Association in 2007, there were more than 23 million Americans living with diabetes. This is a 13.5% increase from 2005, likely representing increases in Type II DM (DMII). Di...

journal_title：Journal of intensive care medicine

authors： Scalea JR,Cooper M

更新日期：2012-07-01 00:00:00

abstract：:Fever after cardiac surgery in children may be due to bacterial infection or noninfectious origin like systemic inflammatory response syndrome (SIRS) secondary to bypass procedure. A marker to distinguish bacterial from nonbacterial fever in these conditions is clinically important. The purpose of our study was to eva...

journal_title：Journal of intensive care medicine

authors： Nahum E,Livni G,Schiller O,Bitan S,Ashkenazi S,Dagan O

更新日期：2012-05-01 00:00:00

abstract：UNLABELLED:While clinicians' management of severe sepsis and septic shock has been positively influenced by a number of clinical research studies in the last decade, challenges remain regarding early hemodynamic optimization as envisioned in the Surviving Sepsis Campaign's (SSC) resuscitation bundle (RB). We examined t...

journal_title：Journal of intensive care medicine

authors： Coba V,Whitmill M,Mooney R,Horst HM,Brandt MM,Digiovine B,Mlynarek M,McLellan B,Boleski G,Yang J,Conway W,Jordan J,(The Henry Ford Hospital Sepsis Collaborative Group).

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Aspiration past the tracheal tube cuff has been recognized to be a risk factor for the development of ventilator-associated pneumonia (VAP). This study investigated the effect of closed tracheal suctioning on aspiration of fluid past the tracheal tube cuff in an in vitro benchtop model. METHODS:High-volume ...

journal_title：Journal of intensive care medicine

authors： Dave MH,Frotzler A,Madjdpour C,Koepfer N,Weiss M

更新日期：2011-09-01 00:00:00

abstract：:Pulmonary embolus (PE) is estimated to cause 200 000 to 300 000 deaths annually. Many deaths occur in hemodynamically unstable patients and the estimated mortality for inpatients with hemodynamic instability is between 15% and 25%. The diagnosis of PE in the critically ill is often challenging because the presentation...

journal_title：Journal of intensive care medicine

authors： Marshall PS,Mathews KS,Siegel MD

更新日期：2011-09-01 00:00:00

abstract：:With the introduction of highly active antiretroviral therapy (HAART), HIV has become a chronic disease. As HIV-infected patients are aging, they are at increased risk for comorbid diseases. These non-AIDS related diseases account for a growing proportion of intensive care unit (ICU) admissions in HIV-infected patient...

journal_title：Journal of intensive care medicine

authors： Akgün KM,Pisani M,Crothers K

更新日期：2011-05-01 00:00:00

abstract：:Realizing the vast medical benefits of validated protocols, recommendations and practice guidelines requires acceptance and implementation by frontline care providers. Knowledge translation is the science of accelerating the transfer of knowledge to practice by understanding and creatively addressing the barriers that...

journal_title：Journal of intensive care medicine

authors： Stoneking L,Denninghoff K,Deluca L,Keim SM,Munger B

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Consensus guidelines support the use of low-molecular-weight heparin for venous thromboembolism (VTE) prophylaxis in high-risk trauma patients but do not recommend a specific regimen. The current study compared the effectiveness and safety of enoxaparin 40 mg once-daily versus enoxaparin 30 mg twice-daily fo...

journal_title：Journal of intensive care medicine

authors： Bush S,LeClaire A,Hampp C,Lottenberg L

更新日期：2011-03-01 00:00:00

abstract：:Extracorporeal membrane oxygenation (ECMO) comprises a commonly used method of extracorporeal life support. It has proven efficacy and is an accepted modality of care for isolated respiratory or cardiopulmonary failure in neonatal and pediatric populations. In adults, there are conflicting studies regarding its benefi...

journal_title：Journal of intensive care medicine

authors： Allen S,Holena D,McCunn M,Kohl B,Sarani B

更新日期：2011-01-01 00:00:00

abstract：:Antibacterial resistance is increasing throughout the world, while the development of new agents is slowly progressing. In addition, the increasing prevalence of fluoroquinolone resistance may force many practitioners to choose an aminoglycoside agent in gram-negative regimens. Aminoglycosides are bactericidal agents ...

journal_title：Journal of intensive care medicine

authors： Radigan EA,Gilchrist NA,Miller MA

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The efficacy of routinely obtained chest radiographs (CXRs) on admission to the intensive care unit (ICU) is largely unknown. The current study investigated the efficacy of routinely obtained admission CXRs and determined whether the value of this diagnostic test was dependent on patient categ...

journal_title：Journal of intensive care medicine

authors： Kager LM,Kröner A,Binnekade JM,Gratama JW,Spronk PE,Stoker J,Vroom MB,Schultz MJ

更新日期：2010-07-01 00:00:00

abstract：:Brain blood flow tests with diffusible radiopharmaceuticals are often done as an ancillary test in brain death (BD). We report a case of an infant with absent brain blood flow on an anterior planar image despite persistent breathing and extensor posturing. We reviewed the literature from 1980 to 2008 using MEDLINE and...

journal_title：Journal of intensive care medicine

authors： Joffe AR,Lequier L,Cave D

更新日期：2010-01-01 00:00:00

abstract：:The aim of the study was to describe our experience with bi-level positive airway pressure (BiPAP) ventilation in oncology children with acute respiratory failure, hospitalized in a single tertiary pediatric tertiary center. This was a retrospective cohort study of all pediatric oncology patients in our center admitte...

journal_title：Journal of intensive care medicine

authors： Schiller O,Schonfeld T,Yaniv I,Stein J,Kadmon G,Nahum E

更新日期：2009-11-01 00:00:00

abstract：:Hyponatremia is one of the newer and emerging risk factors for an adverse prognosis in chronic heart failure. Why decreased serum sodium is associated with worse prognosis remains unclear. It may reflect worsening heart failure and the deleterious effects of activation of neurohormones. The mechanism of hyponatremia i...

journal_title：Journal of intensive care medicine

authors： Chatterjee K

更新日期：2009-11-01 00:00:00

abstract：:Intravascular volume status and volume responsiveness continue to be important questions for the management of critically ill or injured patients. Goal-directed hemodynamic therapy has been shown to be of benefit to patients with severe sepsis and septic shock, acute lung injury and adult respiratory distress syndrome...

journal_title：Journal of intensive care medicine

authors： McGee WT

更新日期：2009-11-01 00:00:00

abstract：AIMS:To investigate the occurrence and etiology of fever at anytime during pediatric intensive care unit (PICU) admission, and to study its possible effects on clinical outcome in a heterogeneous population of critically ill children. METHODS:Retrospective, observational single center study, comprising 202 patients ag...

journal_title：Journal of intensive care medicine

authors： Gordijn MS,Plötz FB,Kneyber MC

更新日期：2009-09-01 00:00:00

abstract：:Bladder pressure measurement through a foley catheter is the current standard in monitoring for intraabdominal hypertension (IAH) and abdominal compartment syndrome (ACS). Accurate pressure transduction requires a continuous fluid column with a small volume of transducing medium at the tip of the catheter. Infusing ex...

journal_title：Journal of intensive care medicine

authors： Kimball EJ,Baraghoshi GK,Mone MC,Hansen HJ,Adams DM,Alder SC,Jackson P,Cannon P,Horn J,Wolfe TR

更新日期：2009-07-01 00:00:00